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Study of the quality of animal research in Switzerland – implications for the ARRIVE guidelines

The reproducibility of preclinical research has been in the limelight over the last few years, with many major scientific stakeholders concerned about the quality of the design and reporting of animal experiments.

The Researchers’ View of Scientific Rigor—Survey on the Conduct and Reporting of In Vivo Research

Reproducibility in animal research is alarmingly low, and a lack of scientific rigor has been proposed as a major cause.

Authorization of Animal Experiments Is Based on Confidence Rather than Evidence of Scientific Rigor

Accumulating evidence indicates high risk of bias in preclinical animal research, questioning the scientific validity and reproducibility of published research findings.